Title Cell Cycle-dependent Expression of Chitin Synthase Genes in Aspergillus nidulans
Author Bum-Chan Park, Pil-Jae Maeng, and Hee-Moon Park*
Address Department of Microbiology, College of Natural Sciences, Chungnam National University, Taejon 305-764, Korea
Bibliography Journal of Microbiology, 39(1),74-78, 2001,
Key Words Aspergillus nidulans; chitin synthase genes; cell cycle; Northern analysis
Abstract The transcription of the chitin synthase genes (chss) was cell cycle-regulated in Aspergillus nidulans and the expression pattern was classified into two groups. Group one, containing chsA and chsC, showed decreasing transcription level upon entry into the S-phase and no further variation during the remainder of the cell cycle. However, group two, containing chsB, chsD, and csmA, showed a sharp decrease of mRNA level upon entry into the G2-phase and an increase during the M-phase. Our results suggested that the chss, belonging to same group with the similar expression pattern during the cell cycle are functionally linked and that chsD may play a role in hyphal growth and development in A. nidulans.
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