| Title | Optimal Fermentation Conditions for Enhanced Glutathione Production by Saccharomyces cerevisiae FF-8 |
|---|---|
| Author | Jae-Young Cha1 , Jin-Chul Park1 , Beong-Sam Jeon 2 , Young-Choon Lee1 and Young-Su Cho1 , * |
| Address | 1 Department of Biotechnology, College of Natural Resources and Life Science, Dong-A University, Busan 604-714, Korea; 2 BioHub Co., Ltd, Institute of Life Science (33)-617, Gyeongsang National University, Jinju, Gyeongnam 660-701, Korea |
| Bibliography | Journal of Microbiology, 42(1),51-55, 2004, |
| DOI | |
| Key Words | L-cysteine, glucose, glutathione, Saccharomyces cerevisiae, yeast |
| Abstract | The influence of feedstock amino acids, salt, carbon and nitrogen sources on glutathione production by Saccharomyces cerevisiae FF-8 was investigated. Glucose, yeast extract, KH_2PO_4, and L-cysteine were found to be suitable feedstock. Highest glutathione production was obtained after cultivation with shaking for 72 h in a medium containing glucose 3.0% (w/v), yeast extract 3.0%, KH_2PO_4 0.06% and L-cysteine 0.06%. The glutathione concentration achieved using this medium increased 2.27-fold to 204 mg/l compared to YM basal medium. |
| Download PDF | 421-10.pdf |