| Title | Genomic Relationship of Salmonella enterica Serovar Typhimurium DT104 Isolates from Korea and the United States |
|---|---|
| Author | Shukho Kim 1 , Sung Guen Chun 1 , Ok Young Lim 1 , Mi Sun Park 1 , Yeon Ho Kang 1 , Yong Ho Park 2 and Bok Kwon Lee 1 , * |
| Address | 1 Laboratory of Enteric Infections, Department of Microbiology, National Institute of Health, Nokbun-dong 5, Seoul 122-701; 2 Department of Veterinary Microbiology and Infectious Diseases, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University, Seoul, Korea |
| Bibliography | Journal of Microbiology, 42(1),14-19, 2004, |
| DOI | |
| Key Words | DT104, IS200, fingerprinting, PFGE, resistance, clonality |
| Abstract | Salmonella enterica serovar Typhimurium DT104 (Salmonella Typhimurium DT104 or DT104) hasbeen emerging as a common pathogen for human in Korea since 1997. In order to compare the genomic relationship and to search for the dominant strains in Korea, we conducted pulsed-field gel electrophoresis (PFGE) and IS200 fingerprinting of 25 epidemiological unrelated isolates from human and animals from Korea and cattle from America. Two Salmonella Typhimurium DT104 isolates from human in Korea and all 8 isolates from American cattle had indistinguishable patterns from the PFGE and IS200 fingerprinting but multidrug-resistant Salmonella Typhimurium isolates, including DT104, from Korean animals had diverse genetic patterns. The data suggest that a dominant DT104 strain might have circulated between Korean and American cattle and that it had a high level of clonality. |
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