Title |
Identification of [sigma]^B-Dependent Promoters Using Consensus-Directed Search of Streptomyces coelicolor Genome |
Author |
Eun-Jin Lee 1 , You-Hee Cho 2 , Hyo-Sub Kim1 and Jung-Hye Roe 1 , * |
Address |
1 School of Biological Sciences and Institute of Microbiology, Seoul National University ; 2 Department of Life Science, Sogang University, Seoul, Korea |
Bibliography |
Journal of Microbiology, 42(2),147-151, 2004,
|
DOI |
|
Key Words |
: osmotic stress, differentiation, sigma B ([sigma]^B), Streptomyces coelicolor |
Abstract |
[sigma]^B plays an important role in both osmoprotection and proper differentiation in Streptomyces coelicolor A3(2). We searched for candidate members of the [sigma]^B regulon from the genome database, using the consensus promoter sequence (GNNTN_14-16GGGTAC/T). The list consists of 115 genes, and includes all the known [sigma]^B target genes and many other genes whose functions are related to stress protection and differentiation. |
Download PDF |
14.pdf |