Title |
DD1.5k, the Gene Preferentially Expressed in Bloodstream Isolates of Vancomycin-Resistant Enterococcus faecium |
Author |
Seung-Han Kim1, Dong-Gun Lee2, Jin-Hong Yoo 2 , Su-Mi Choi 2 , Jung-Hyun Choi 2 , Wan-Shik Shin 2 , * , Kyungwon Lee 3 , Dongeun Yong 3 , Wee Gyo Lee 4 , Byung-S. Youn5 and Moon-Won Kang 2 |
Address |
1 Clinical Research Institute, and; 2 Department of Internal Medicine, The Catholic University of Korea, Seoul, 150-713, Korea; 3 Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, 120-749, Korea; 4 Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, 442-749, Korea; 5 KOMED Institute for Life Science, Graduate School of Biotechnology, Korea University, Seoul, 136-701, Korea |
Bibliography |
Journal of Microbiology, 42(2),143-146, 2004,
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DOI |
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Key Words |
Enterococcus, Vancomycin Resistance, Virulence Factors |
Abstract |
Vancomycin-resistant Enterococcus faecium (VREFM) is becoming a threatening pathogen. We identified a gene called DD1.5K by differential display-PCR, which was preferentially expressed in the bloodstream isolates of VREFM. Due to its amino acid similarity to transfer complex protein, trsE, and tissue-specific expression, this gene may be involved in virulence of VREFM. |
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