| Title |
Nematicidal Activity and Chemical Component of Poria cocos |
| Author |
Guo Hong Li1, Yue Mao Shen2, and Ke Qin Zhang 1,*
|
| Address |
1Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, Kunming 650091, P. R. China, 2The State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P. R. China |
| Bibliography |
Journal of Microbiology, 43(1),17-20, 2005,
|
| DOI |
|
| Key Words |
Poria cocos, nematicidal activity, nematicidal fungi, structural analysis |
| Abstract |
Poria cocos, a famous traditional Chinese medicine, was found to have nematicidal activity in experiments searching for nematicidal fungi. The experiment showed it could kill 94.9% of the saprophytic nematode, Panagrellus redivivue, 92.6% of the root-knot nematode, Meloidogyne arenaria, and 93.5% of the pine nematode, Bursaphelenchus xylophilus, on PDA plate within 12 hours. According to the nematicidal activity, three new compounds, 2, 4, 6-triacetylenic octane diacid, 2, 4, 5, 6-tetrahydroxyhexanoic acid and 3, 4-dihydroxy-2-keto-n-butyl 2,4,5,6-tetrahydroxyhexanate, were isolated from submerged cultures of Poria cocos. Of these, 2, 4, 6-triacetylenic octane diacid could kill 83.9% Meloidogyne arenaria and 73.4% Panagrellus redivivus at 500 ppm within 12 hours. Here, it is reported for the first time that Poria cocos has nematicidal activity. |
| Download PDF |
p[1].17-20.pdf |
