| Title | Analysis of Substitution Events in HIV-1 vif Gene of the Korean Clade |
|---|---|
| Author | Chan Seung Park1, Mi Sook Kim1, Hyun Ah Yi1, Dong Hun Lee1, Keon Myung Lee2, and Chan Hee Lee1* |
| Address | 1School of Life Sciences Chungbuk National University, Cheongju, Republic of Korea, 2School of Electrical and Computer Engineering, Chungbuk National University, Cheongju, Republic of Korea |
| Bibliography | Journal of Microbiology, 45(1),75-78, 2007, |
| DOI | |
| Key Words | HIV-1, vif, Korean clade, substitution ratio |
| Abstract | Nucleotide and amino acid substitution pattern in vif gene of the Korean clade of HIV-1 isolated from Koreans were analyzed using consensus sequences. At nucleotide level, transition/transversion substitution ratio was 1.88, and nonsynonymous/synonymous substitution ratio was 2.67, suggesting a divergent <br>evolution in the Korean clade. At amino acid level, there were 17 substitutions and G→E substitution at position 37 may be responsible for change in predicted secondary structure. |
| Download PDF | JM45(1)-14.pdf |