| Title | The Antimicrobial Activity of Essential Oil from Dracocephalum foetidum against Pathogenic Microorganisms |
|---|---|
| Author | Saet Byoul Lee1, Kwang Hyun Cha1, Su Nam Kim1, Shataryn Altantsetseg2, Sanduin Shatar2, Oidovsambuu Sarangerel3, and Chu Won Nho1* |
| Address | 1Natural Products Research Center, KIST Gangneung Institute, Gangneung Techno Valley, Gangneung, Gangwon-do, Republic of Korea, 2Institute of Chemical and Chemical Technology, Ulaanbaatar-51, Mongolia, 3Mongolian National University, Ulaanbaatar, Mongolia |
| Bibliography | Journal of Microbiology, 45(1),53-57, 2007, |
| DOI | |
| Key Words | Dracocephalum foetidum, essential oil, antimicrobial activity, volatility, n-Mentha-1,8-dien-10-al, limonene |
| Abstract | A number of essential oils from Mongolian aromatic plants are claimed to have antimicrobial activities. The essential oil of Dracocephalum foetidum, a popular essential oil used in Mongolian traditional medicine, was examined for its antimicrobial activity. Eight human pathogenic microorganisms including B. subtilis, S. aureus, M. lutens, E. hirae, S. mutans, E. coli, C. albicans, and S. cerevisiae were examined. The essential oil of Dracocephalum foetidum exhibited strong antimicrobial activity against most of the pathogenic bacteria and yeast strains that were tested; by both the agar diffusion method and the minimum inhibitory concentration (MIC) assay (MIC range was 26-2592 μg/ml). Interestingly, Dracocephalum foetidum even showed antimicrobial activity against methicilin-resistant Staphylococcus aureus (MRSA) strains. We also analyzed the chemical composition of the oil by GC-MS and identified several major components, including n-Mentha-1,8-dien-10-al, limonene, geranial, and neral. |
| Download PDF | JM45(1)-10.pdf |