Title Classification of Hybrid and Altered Vibrio cholerae Strains by CTX Prophage and RS1 Element Structure
Author Je Hee Lee1,2, Seon Young Choi1,2, Yoon-Seong Jeon1,2, Hye Ri Lee1, Eun Jin Kim1, Binh Minh Nguyen3, Nguyen Tran Hien3, M. Ansaruzzaman4, M. Sirajul Islam4, Nurul A. Bhuiyan4, S.K. Niyogi5, B.L. Sarkar5, G. Balakrish Nair5, Dae Shick Kim6, Anna Lena Lopez1, Cecil Czerkinsky1, John D. Clemens1, Jongsik Chun1,2, and Dong Wook Kim1*
Address 1International Vaccine Institute, Seoul 151-919, Republic of Korea, 2School of Biological Sciences, Seoul National University, Seoul 151-747, Republic of Korea, 3National Institute of Hygiene and Epidemiology, Hanoi 10,000, Vietnam, 4International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh, 5National Institute of Cholera and Enteric Diseases, Kolkata 700 010, India, 6Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Republic of Korea
Bibliography Journal of Microbiology, 47(6),783-788, 2009,
DOI
Key Words V. cholerae, biotype, altered strain, hybrid strain, CTX prophage, RS1 element
Abstract Analysis of the CTX prophage and RS1 element in hybrid and altered Vibrio cholera O1 strains showed two classifiable groups. Group I strains contain a tandem repeat of classical CTX prophage on the small chromosome. Strains in this group either contain no element(s) or an additional CTX prophage or RS1 element(s) on the large chromosome. Group II strains harbor RS1 and CTX prophage, which has an El Tor type rstR and classical ctxB on the large chromosome.