| Title |
Emergence of Vancomycin-Intermediate Staphylococcus aureus from Predominant Methicillin-Resistant S. aureus Clones in a Korean Hospital |
| Author |
Hwa Yun Cha1, Hyun Ok Kim1, Jong Sook Jin2, and Je Chul Lee2* |
| Address |
1Health and Environment Institute of Daegu, Daegu 706-706, Republic of Korea, 2Department of Microbiology, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea |
| Bibliography |
Journal of Microbiology, 48(4),533-535, 2010,
|
| DOI |
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| Key Words |
MRSA, VISA, sequence type, SCCmec |
| Abstract |
The genetic and epidemiological features of four vancomycin-intermediate Staphylococcus aureus (VISA) isolates obtained from a Korean hospital were evaluated in this study. The VISA isolates were genotyped as sequence type (ST) 5-staphylococcal cassette chromosome mec (SCCmec) II variant (n=2) and ST239- SCCmec III (n=2), which were derived from the predominant methicillin-resistant S. aureus (MRSA) clones in Korean hospitals. One VISA isolate was acquired during vancomycin treatment, whereas three VISA isolates were obtained from the patients who had not previously been exposed to glycopeptides. As VISA is likely to arise from the predominant MRSA clones and may then possibly spread between patients, the emergence of VISA should be monitored with great care in hospitals. |
