Title Antimicrobial Effect of Korean Propolis Against the Mutans Streptococci Isolated from Korean
Author Min Jung Kim1, Chun Sung Kim1, Byung-Hoon Kim2, Sang-Bok Ro2, Yun Kyong Lim1, Soon-Nang Park1, Engene Cho1, Jang-Hyuk Ko2, Soon-Sung Kwon2, Yeong-Mu Ko2, and Joong-Ki Kook1*
Address 1Department of Oral Biochemistry, School of Dentistry, Chosun University, Gwangju 501-759, Republic of Korea, 2Department of Dental Materials, School of Dentistry, Chosun University, Gwangju 501-759, Republic of Korea
Bibliography Journal of Microbiology, 49(1),161-164, 2011,
DOI
Key Words antimicrobial effect, propolis, mutans streptococci, Koreans
Abstract The aim of this study was to determine the optimal concentration of Korean propolis against clinical isolates of mutans streptococci (MS) from Koreans. The antimicrobial activity was evaluated using the minimum inhibitory concentration (MIC) and time-kill curves against mutans streptococci. The MIC90 values of propolis for MS were 35 μg/ml. Propolis had a bacteriostatic effect on Streptococcus mutans ATCC 25175T and bactericidal effects on Streptococcus sobrinus ATCC 33478T at > 2×MIC (70 μg/ml). These results suggest that the propolis can be used in the development of oral hygiene products for the prevention of dental caries.