| Title | NOTE] Is The Biotransformation of Chlorinated Dibenzo-p-dioxins by Sphingomonas wittichii RW1 Governed by Thermodynamic Factors? |
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| Author | In-Hyun Nam1*, Hyo-Bong Hong2, and Stefan Schmidt3 |
| Address | 1Geologic Environment Division, Korea Institute of Geoscience and Mineral Resources (KIGAM), Daejeon, 305-350, Republic of Korea, 2Future Technology Research Group, Electronics and Telecommunications Research Institute (ETRI), Daejeon 305-700, Republic of Korea, 3Discipline of Microbiology, School of Life Sciences, University of KwaZulu-Natal, Pietermaritzburg 3201, South Africa |
| Bibliography | Journal of Microbiology, 52(9),801–804, 2014, |
| DOI | 10.1007/s12275-014-3424-6 |
| Key Words | dibenzo-p-dioxin, biotransformation rates, Sphin-gomonas wittichii RW1, DFT calculation, correlation analysis |
| Abstract | Density functional theory (DFT) calculations were used to explore the relationship between the biotransformation of dibenzo-p-dioxin and selected chlorinated derivatives by resting cells of Sphingomonas wittichii RW1 and measuring the thermodynamic properties of the biotransformation substrates. Sphingomonas wittichii RW1 can aerobically catabolize dibenzo-p-dioxin as well as 2,7-dichloro-, 1,2,3-trichloro-, 1,2,3,4-tetrachloro-, and 1,2,3,4,7,8-hexachlorodibenzo-pdioxin; however, neither the 2,3,7-trichloro- nor the 1,2,3,7,8-pentachlorodibenzo-p-dioxin was transformed to its corresponding metabolic intermediate. The experimental biotransformation rates established were apparently governed by the selected thermodynamic properties of the substrates tested. |