Title Minireview] Microbial radiation-resistance mechanisms
Author Kwang-Woo Jung1, Sangyong Lim1*, and Yong-Sun Bahn2*
Address 1Research Division for Biotechnology, Korea Atomic Energy Research Institute, Jeongeup 56212, Republic of Korea, 2Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea
Bibliography Journal of Microbiology, 55(7),499–507, 2017,
DOI 10.1007/s12275-017-7242-5
Key Words radiation, DNA damage, reactive oxygen species, antioxidant mechanism, microorganism
Abstract Organisms living in extreme environments have evolved a wide range of survival strategies by changing biochemical and physiological features depending on their biological niches. Interestingly, organisms exhibiting high radiation resistance have been discovered in the three domains of life (Bacteria, Archaea, and Eukarya), even though a naturally radiationintensive environment has not been found. To counteract the deleterious effects caused by radiation exposure, radiation- resistant organisms employ a series of defensive systems, such as changes in intracellular cation concentration, excellent DNA repair systems, and efficient enzymatic and non-enzymatic antioxidant systems. Here, we overview past and recent findings about radiation-resistance mechanisms in the three domains of life for potential usage of such radiationresistant microbes in the biotechnology industry.