| Title | [Minireview]The rationale and potential for using Lactobacillus in the management of periodontitis |
|---|---|
| Author | Jiaqi Wang1, Yingman Liu1, Weiru Wang1, Jiaojiao Ma1, Manman Zhang2, Xiaoying Lu2, Jie Liu3, and Yurong Kou1,2* |
| Address | 1Department of Periodontics, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang 110122, P. R. China, 2Department of Oral Biology, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang 110122, P. R. China, 3Science Experiment Center, China Medical University, Shenyang 110122, P. R. China |
| Bibliography | Journal of Microbiology, 60(4),355-363, 2022, |
| DOI | 10.1007/s12275-022-1514-4 |
| Key Words | periodontitis, probiotic, Lactobacillus |
| Abstract | Periodontitis refers to a wide range of the inflammatory conditions of supporting dental structures. For some patients with periodontitis, antibacterial agents are needed as an adjuvant to mechanical debridement treatments and oral hygiene maintenance. However, the widespread use of broad-spectrum antibiotics for the prophylaxis and treatment of periodontal infections results in the emergence of resistant pathogens. Therefore, probiotics have become markedly interesting to researchers as a potentially safe alternative to periodontal treatment and maintenance. Probiotics have been used in medicine for decades and extensively applied to the treatment of inflammatory diseases through the modulation of microbial synergy and other mechanisms. A growing amount of evidence has shown that using Lactobacillus strains for oral cavity maintenance could improve periodontal health. In this study, we reviewed studies showing proof of the inhibitory effects of Lactobacillus species on periodontal inflammation. We also explored the rationale and potential for using Lactobacillus species in the management of periodontitis. |