| Title | Characterization of the nature of virulency caused by vibrio anguillarum : Identification of an outer membrane protein rendering virulency | ||
| Author | Lee, Jong Soo · Jeong, Ga Jin * · Hah, Yung Chil | ||
| Address | Department of Microbiology, and Research Center for Molecular Microbiology, Seoul National University | ||
| Bibliography | Korean Journal of Microbiology, 32(6),531-538, 1994 | ||
| DOI | |||
| Key Words | Vibrio anguillarum, vibriosis, outer membrane proteins, proteolytic activity | ||
| Abstract | Virulent factors from two strains of a fish pathogenic microorganism, Vibrio anguillarum, V7 and V104, have been studied to identify the nature of virulency and mechanism of pathogenicity. The most virulent strain V7 (serotype J01) was compared for various characteristic with less virulent one V104 (serotupe J03). The effect of temperature on the reduction of virulency of V. anguillarum was critical above the optimal temperature, regardless of the strains ever tested. The optimal temperature for virulency induction was 22~24℃. Dramatic decrease of 41kd outer membrane protein in V7 grown at 32℃ suggested the possibility that this protein might be associated with the cirulency, where 31 kd one from V104 was not so significant in rendering virulency even if it was also reduced when frown at high temperature. Strain V7 showed serum resistance, hemagglutinating activity, and proteolytic activity. It is not clear yet if strains V7 and V104 have different mechanisms of pathogenicity, but it is likely that the cirulency of the strain V7 could be directly related to the expression of 41 kd protein. | ||
| Download PDF | Kor_320614_531-538p.pdf | ||