| Title | Klebsiella aerogenes의 카드뮴 적응 및 해독기작에 관련된 생리생화학적인 변화 | ||
| Author | 이기성1 · 송인근 · 박영식1 · 윤성녀 · 최영길 | ||
| Address | 1배재대학교 생물학과; 한양대학교 생물학과 | ||
| Bibliography | Korean Journal of Microbiology, 28(3),249-257, 1990 | ||
| DOI | |||
| Key Words | phosphatase, derepression, phospholipid, nucleotide pool, defence | ||
| Abstract | In the course of operating the accommodative and detoxifying mechanism against cadmium, its physio-biochemical changes were observed in Klebsiella aerogenes ATCC 10031. Changes of enzyme activity concerned phosphate metabolism, changes of phospholipid composition and in view of energy metabolism the changes of the nucleotide pool were examined. Activities of both alkaline and acid phosphatase were derepressed 4-10 folds under cadmium added cultures. Moreover, production of phospholipid such as lysophosphatidyl choline (LPC), phosphatidyl serine (PS) and phosphatidyl ethanolamone (PE) was increased and uridylate nucleotide pool was increased under Cd-surplus culture. These results i.e. overproduction of phosphatase catalyzing phosphate residue, increase of the production of PE and PS which have a close affinity with cadmium, and increase of uridylate nucleotide pool used as a carrier of polysaccharide synthesis like bacterial capsule exhibited cellular responses for active defence against Cd-pressure. It was postulated that these phenomena should play another assistant roles in Cd-detoxifing mechanism. | ||
| Download PDF | Kor_280311_249-257p.pdf | ||