Title Vibrio vulnificus Lipopolysaccharide의 생물학적 특성과 Escherichia coli 및 Salmonella typhimurium의 Lipopolysaccharides와의 비교 연구
Author 김용호 · 이봉헌 · 신흥대 · 강신원
Address 부산대학교 자연과학대학 화학과
Bibliography Korean Journal of Microbiology, 27(2),147-154, 1989
DOI
Key Words Vibrio vulnificus, E. coli, Salmonella typhimurium, Lipopolysacchrides
Abstract Vibrio vulnificus Lipopolysaccharide (LPS) was extracted, performed chemical analysis, tested its biological activities, and compared to those of Escherichia coli LPS and Salmonella typhimurium LPS. The lethal activity of V. vulnificus LPS was 138.6138.6 mg/kg in mouse, but this was lower than thowe of E. coli LPS (56.3 mg/kg) and S. typhimurium LPS (37.5 mg/kg). The result of fatty acid analysis showed that V. vulnificus LPS had more saturated fatty acid than E. coli LPS and S. typhimurium LPS. Above results indicated that V. vulnificus LPS did not have much effect on the lethality. The results of biological responses of enzymes and blood cells by LPSs showed that V. vulnificus LPS had slightly greater activity than E. coli LPS and S. typhimurium LPS. V. vulnificus LPS was recommendavle for stimulant on interferon induction because of adequate stimulation and safety for host and cell lines.
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