| Title | 효모의 접합과정에 관여하는 유전자의 연구 | ||
| Author | 장광엽 · 박문국 * · 정봉우 ** | ||
| Address | 전북대학교 생물학과; * 전북대학교 생물교육학과; ** 전북대학교 화공공학과 | ||
| Bibliography | Korean Journal of Microbiology, 27(3),210-215, 1989 | ||
| DOI | |||
| Key Words | Saccharomyces cerevisiae, mating pheromone signal, CDC. | ||
| Abstract | In order to elucidate and characterize the signal transduction pathway(s) whereby yeast cells respond to mating pheromone, we have isolated mutants which are able to conjugate in the absence of the alpha-factor receptor. Sixty-one suppressors of a ste2-deletion mutation which also confer a ts conditional "start" arrest phenotype have been subjected to genetic analysis. The mutants could be assigned to three complementation groups designated CDC70, CDC72 and CDC73, which are unlinked to each other as well as to the previously identified start genes. Quantitation of mating ability of the cdc70, cdc72 and cdc73 mutations in a ste2-deletion background gives levels ranging from 0.1% to 0.3% of wild type, depending on the allele and the gene. The results indicate that the signals from mating pheromone might be mediated by the CDC70, CDC72 and CDC73 products. | ||
| Download PDF | Kor_270307_210-215p.pdf | ||