| Title | Moloney murine Leukemia Virus에서 포장신호의 가능한 3' 끝의 염기서열 | ||
| Author | 박종상 | ||
| Address | 서울대학교 자연과학대학 화학과 | ||
| Bibliography | Korean Journal of Microbiology, 26(2),101-105, 1988 | ||
| DOI | |||
| Key Words | deletion mutants around packaging signal, transfection, resistant cells, 10 base pair stem structure | ||
| Abstract | 6M-MuLV mutants containing deldtions around the putative packaging signal were constructed by using recombinant DNA technique and transfected into NIH/3T3 cell. 2 of 6 mutants can not be packaged into virions even in the presence of the wild type helper virus. The boundary between the packagible and the non-packagible genome is located around Pvu I site, 421 nucleotide downstream from the 5' end of M-MuLV genome. 10 base pair inverted repeat sequence (GAGUCCAAAA) which can make stem structure around Pvu I site could be the putative packaging signal. | ||
| Download PDF | Kor_260205_101-105p.pdf | ||