Title Mannose permease가 변형된 대장균 변이주에 대한 coliphage N4 감염의 저해
Author 김기태 · 유욱준
Address 한국과학기술원 생물공학과
Bibliography Korean Journal of Microbiology, 25(3),184-188, 1987
DOI
Key Words N4 phage, pel mutant, mannose permease, host range mutant phage
Abstract Evidences that the mannose permease of Escherichia coli mediates the infection of N4 in early steps, were obtained as follows. First, A mutant strain of Escherichia coli which was resistant to both wild type N4 and lambda whose genome is Charon 4A containing human genomic fragments in its EcoR I site, could not use mannose efficiently. Second, N4 could not infect pel mutant strains which lack one or all of intact components of mannose permease. However, unknown alterations in N4 made it possible for the phage to infect pel mutant of E. coli. It also turned out to be clear that the receptor of N4 was different from that of lambda.
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