Title Aspergillus nidulans의 역제의 유전자의 작용기작에 관한 연구 II
Author 문은표 · 강현삼
Address 서울대학교 자연대학 미생물학과
Bibliography Korean Journal of Microbiology, 20(1),1-10, 1982
Key Words Studies on the machanisms of suppression in Aspergilllus nidulans; II. The characteristics of the suppressors for acriflavin resistant and nicotinamide auxotrophic phenotypes
Abstract From Aspergillus nidulans, six suppressor mutants, MSI-MS6, were isolated, and their characteristics were analysed. These were the suppressor mutants for acriflavin resistant and nicotinamide auxotrophic mutant phenotypes. MS1, MS2, MS5 and MS6, were linked to the chromosome IV, I, II respectively, and MS2 was linked to one of the rest chromosomes, MS3 and MS6 mutants had both suppressors for acriflavin resistant marker and for nicotinamide auxotrophic marker. In order to know the stability and efficiency of the suppressors, their reversion frequencies, that is, frequencies of losing the suppressibility, were analysed. Only MS3 and MS5 were reversed with high frequency. The four mutants didn't lose their suppressibilities, and this meant that the suppressors of these four were very stable and highly efficient. The suppressor specificities of these mutants were tested for other mutant's phenotype marker. One of the six suppressors, MS1, had the suppressor specificity for acriflavin resistant marker of 163 strain.
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