Title Salmonella typhimurium내로의 pKM101 돌연변이체의 유도와 그 특성에 관한 연구
Author 백형석 · 강수형 · 이세영
Address 고려대학교 농과대학 농화학과
Bibliography Korean Journal of Microbiology, 20(2),89-97, 1982
DOI
Key Words Induction and chatacterization of pKM101 mutants in salmonella typhimurium
Abstract Mutants of plasmid pKM101 modified to enhance mutagenesis were induced and characterized in Salmonella typhimurium. The pKM101 mutant plasmid were transferred normally and stably maintained in cells. They had modified in their ability (i) to enhance the reversion of both point and frameshift mutations, (ii) to protect the cell against UV-irradiation and chemical mutagen treatment, (iii) of ampicillin resistance. A similar modification in enhancement of reversion was also observed in a uvr B-strains. These results indicated that mutator effect of pKM101 was coded by one plasmid gene.
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