Title Streptomyces의 aerial mycelium 형성에 대한 glucose 억제 기작에 관한 연구
Author 김재헌 · 김웅진 · 강현삼 · 하영칠 · 홍순우
Address 서울대학교 자연과학대학 미생물학과
Bibliography Korean Journal of Microbiology, 18(3),115-122, 1980
DOI
Key Words The glucose repression of aerial mycelium formation in streptomyces
Abstract We have demonstrated that both L-histidine as an amino acid factor and dextrin as a carbon source were required for the glucose repression. 1% glucose was sufficient to the glucose repression of aerial mycelium formation in Streptomyces lavendulae and Streptomyces aureofacience. The synthesized medium, KK, which is lack of all organic nutrients except dextrin was able to induce glucose repression, but the addition of 0.003% or more L-histidiner recovers the capacity of glucose repression. 0.02% or more histidine was reuqired for glucose repression of aerial mycelium formation in the absence of dextrin. Treatments of 5.mu.M or more ethidium bromide (EtBr0 gave rise to bald mutants at high frequency in Streptomyces aureofaciens, and it is probable that the gene(s) for the function of aerial mycelium formation is linked to plasmid DNA in this species
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