| Title | Isolation of secondary metabolites from an Arctic bacterium, Pseudomonas aeruginosa and their antimicrobial activities | ||
| Author | Ui Joung Youn*, Min Ju Kim, Se Jong Han, and Jung Han Yim | ||
| Address | Division of Life Sciences, Korea Polar Research Institute, KIOST, Incheon 21990, Republic of Korea | ||
| Bibliography | Korean Journal of Microbiology, 52(4),415-420, 2016 | ||
| DOI | https://doi.org/10.7845/kjm.2016.6058 | ||
| Key Words | Pseudomonas aeruginosa, antimicrobial activity, diketopiperazine, phenazine, Pseudomonadaceae | ||
| Abstract | Chemical study of an Arctic bacterium, Pseudomonas aeruginosa (Pseudomonadaceae) led to the isolation of two diketopiperazines 1 and 2, two phenazine alkaloids 3 and 4, and an indole carbaldehyde 5, along with a benzoic acid derivative 6. The structures of the compounds were confirmed by 1D and 2D NMR, and MS experiments, as well as by comparison of their data with published values. Among the isolates, compounds 5 and 6 were isolated for the first time from P. aeruginosa of the seawater of Arctic Chuckchi Sea. Antimicrobial activities of compounds 1‒6 against a Staphylococcus aureus and Candida albicans were evaluated. | ||
| Download PDF | 52(4)_04_415-420.pdf | ||