| Title | Selection of model viruses for foot-and-mouth disease virus-related-experiments | ||
| Author | Tae-Hwan Kim1, Thilina U. B. Herath1, Jae-Hoon Kim1, Kwang-Nyeong Lee2, Jong-Hyeon Park2, Chul-Joong Kim1, and Jong-Soo Lee1* | ||
| Address | 1College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Republic of Korea, 2Foot and Mouth Disease Division, Animal Quarantine and Inspection Agency, Gimcheon 39660, Republic of Korea | ||
| Bibliography | Korean Journal of Microbiology, 53(4),304-308, 2017 | ||
| DOI | https://doi.org/10.7845/kjm.2017.7069 | ||
| Key Words | bovine rhinovirus, FMDV-like virus, foot-andmouth disease virus, human rhinovirus, model viruses | ||
| Abstract | Researchers have comparatively fewer opportunities to conduct experiments on foot-and-mouth disease virus (FMDV), owing to the limited availability of biosafety level 3 facilities. Bovine rhinovirus (BRV) and human rhinovirus (HRV), which are genetically closely related to FMDV, have been evaluated in this study as model viruses for FMDV. To discover whether BRV and HRV have similar physicochemical properties as FMDV, virus susceptibility tests have been performed in different physical (pH and heat) and chemical (acidic/alkaline solutions and commercial disinfectants) conditions in vitro. Our data revealed that the physicochemical characteristics of BRV and HRV were nearly similar to those of FMDV. | ||
| Download PDF | 10_[304-308]17-069.pdf | ||