Title The Molecular Characterization of Serogroup C Neisseria meningitidis Strains Circulating in Beijing
Author Tie-gang Zhang1*, Jing-guo He1, Xiong He1, Li-Juan Chen1, Zhu-jun Shao2, and Mei-ping Sun1
Address 1Institute of Immunization and Prevention, Beijing Center for Disease Prevention and Control. 16, Hepingli Middle Avenue, Dongcheng District, Beijing 100013, China, 2Institute for Communicable Disease Control and Prevention, China CDC, 5 Liuzi, Changping District, Beijing 102206, China
Bibliography Journal of Microbiology, 44(6),685-688, 2006,
DOI
Key Words Multilocus sequence typing, Pulsed-field gel electrophoresis, Serosubtype, Serotype Serogroup C Neisseria meningitides
Abstract The aim of this study was to characterize the molecular features of serogroup C Neisseria meningitidis strains circulating in Beijing, China. Twenty out of 23 strains belonged to ST 4821. The causative serosubtype for meningococcal meningitis was P1.12-1,16-8. All of the strains expressed class 3 PorB protein. Among the five pulsed-field gel electrophoresis patterns observed, pattern III predominated.
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