| Title |
NOTE] Involvement of Curli Fimbriae in the Biofilm Formation of Enterobacter cloacae |
| Author |
Sung-Min Kim1,2, Hee-Woo Lee1,3, Yeh-Wan Choi1, Shuk-Ho Kim1, Je-Chul Lee1, Yoo-Chul Lee1, Sung-Yong Seol1, Dong-Taek Cho1, and Jungmin Kim1* |
| Address |
1Department of Microbiology, School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea, 2Present address: †Division of Magnetic Resonance Research, Korea Basic Science Institute, Chungbook 363-883, Republic of Korea, 3Present address: ‡Department of Veterinary Internal Medicine, College of Veterinary |
| Bibliography |
Journal of Microbiology, 50(1),175-178, 2012,
|
| DOI |
|
| Key Words |
curli, biofilm, Enterobacter cloacae |
| Abstract |
In this study, we examined the biofilm forming ability, the
mRNA expression of curli genes and the morphologies of
curli fimbriae and biofilms in clinical isolates of Enterobacter
cloacae. The csgBA operon was found in 11 (78.6%) of the
14 isolates. The ability of E. cloacae isolates to form biofilms
was significantly correlated with the mRNA expression level
of the csgA and csgD genes. The curli protein fimbriae appeared
as tangled fibers and the curli-proficient strain formed
mature biofilms. Our data suggest that the expression of the
curli fimbriae play an important role in biofilm formation
in E. cloacae. |
