Title |
NOTE] Comparison of the Genetic Structures Surrounding qnrA1 in Korean Enterobacter cloacae and Chinese Escherichia coli Strains Isolated in the Early 2000s: Evidence for qnrA Mobilization via Inc HI2 Type Plasmid |
Author |
Sang Hoon Han1, Young Ah Kim2, Minggui Wang3, Yangsoon Lee4, Hae-Sun Chung4, Jong Hwa Yum5, Dongeun Yong4*, Kyungwon Lee4, and June Myung Kim1 |
Address |
1Department of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul 120-752, Republic of Korea , 2Department of Laboratory Medicine, National Health Insurance Corporation Ilsan Hospital, Gyeonggi-do 410-719, Republic of Korea, 3Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai 200040, P. R. China , 4Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul 120-752, Republic of Korea , 5Department of Clinical Laboratory Science, Dong-eui University, Busan 614-714, Republic of Korea |
Bibliography |
Journal of Microbiology, 50(1),166-169, 2012,
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DOI |
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Key Words |
qnrA1, plasmid, plasmid-mediated quinolone resistance, gene mobilization |
Abstract |
The flanking genetic structure of qnrA1 in Korean Enterobacter
cloacae was identical to that of the Chinese Escherichia
coli strain, the first qnrA1-carrying strain reported in Asia.
Analysis of restriction enzyme sites and Southern blot
hybridization results showed that qnrA1 was transferred
between E. cloacae and E. coli via Inc HI2 type plasmid. |